Homologous RecombinationAuthor :
Hardback
Published : Wednesday 26 August 2020
Description
This volume explores homologous recombinations (HR) essential role in meiotic and somatic cells. It discusses the analysis of different steps of the HR process from the genetic, molecular biology, and cell biology perspectives. Using a variety of model systems, chapters in this book cover topics such as the genome-wide mapping of DNA double-strand breaks (DSB); analysis of DNA-end resection and recombination intermediates by gel electrophoresis and southern blotting; cell-based monitoring of HR activity in meiotic and mitotic cells; in vitro analysis of branch migration, DNA strand exchange and Holliday junction resolution; or super resolution imaging of HR repair at collapsed replication forks. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Homologous Recombination: Methods and Protocols is a valuable resource that uses both classical and more recent approaches to answer questions on the HR mechanism. It is a useful tool for scientists working on the field of genome integrity, as well as those working in cancer biology and DNA repair.
You may also like ...
by
Paperback
26 Aug 2021
Medical genetics
€163.79
Extended stock – Dispatch 5-7 days
by
Hardback
26 Aug 2020
Medical genetics
€233.99
Extended stock – Dispatch 5-7 days
by
Paperback
08 Apr 2023
Chakras, auras and spiritual energy
€21.05
Extended stock – Dispatch 5-7 days
by
Hardback
22 Feb 2022
Films, cinema
€93.60
Extended stock – Dispatch 5-7 days
Reviews