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In recent years it has become increasingly obvious that PD is more than a disorder of movement with pathology localized to the dopaminergic nigrostriatal pathway. This book therefore seeks to take this discussion into this new area of research and define the nature of the non-dopaminergic features of PD in a new and exciting way. This includes joint discussions by clinicians and pathologists in many chapters to highlight how one disciple can inform the other and by so doing the chapters have an integrated and complete analysis of the topic under discussion.