Patient Derived Tumor Xenograft Models

Author : Elisa de Stanchina,Rajesh Uthamanthil

Paperback

Published : Wednesday 2 November 2016

ISBN : 9780128040102

Price : €121.68

Description

Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains. In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory.

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